The saffron extract that matches the science
Choose the saffron extract that corresponds to most of the clinical studies, supported as well by the internal study versus Imipramine.
Because of its other branded and patented product Satiereal®, Inoreal is a very important player in the saffron market - undoubtedly the leading European producer for food supplements - and Saffron extracts. Based on this experience and their preferred access to the Sargol vintage from Iranian saffron, Inoreal has developed Moodreal®, the extract that provides safranal (2%) as well as crocin and picrocrocin.
Moodreal® is extracted from Sargol Saffron Stigmas, using water ethanolic process of extraction as per the extracts described in the science and the studies.
 |
Moodreal® a potent SRI, studied versus Imipramine Moodreal® showed an inhibition potency of Serotonin re-uptake equivalent to 63% of Imipramine (TOFRANIL® a “golden standard” Selective Serotonin Reuptake Inhibitor (SSRI), used as antidepressive medication and considered as the reference compound in inhibiting 100% of Serotonin reuptake. An Inhibition over 50% of Serotonin reuptake in this test that demonstrates a significant effects of SSRI. |
Moodreal® matches exactly the extracts described in studies that most players refer to, including those describing activity against stress and depression, versus imipramine and fluoxetine (ie. Prozac®), etc…. For example, published clinical studies confirm that:
- The effectiveness of hydroethanolic saffron extract (15mg x 2 / d saffron ext. >2% safranal) is similar to fluoxetine (Prozac®, 20mg / d) - 6 weeks, 40 adults, depression scoring >18(1)
- In an other study (6 weeks, 30 adults, depression scoring >18), hydroethanolic saffron extract (10mg x 3 / d saffron ext. >2% safranal) is as efficient as the tricyclic antidepressant Imipramine (Tofranil®, 100 mg/d ), without any side effects (3).
- Iranian Saffron Sargol significantly relieves anxiety and depressive symptoms, at a dose of 30 mg / day and within one week (4), and again in 2019 on 57 obese adults (Depression scoring +/- 22 Beck Depression).
- Serotonin Reuptake Inhibition equivalent to 63% of Imipramine
See the product sheet : Moodreal product sheet
Download the leaflet : Leaflet Moodreal