Nigellin® is effective and well-tolerated against symptoms of allergic rhinitis
This new study demonstrates that Nigellin® - Nigella sativa by Sabinsa - 250 mg with 2.5 mg piperine is an effective and well-tolerated supplement for the management of allergic rhinitis symptoms.
Allergic rhinitis (AR) or seasonal allergy characterized by sneezing, nasal congestion, nasal itching, and nasal discharge, triggered by immune reactions to environmental allergens. Present day customers also monitor the personal improvements in the area of Evidence-Based natural medicines/supplements.
A randomized, double-blind, placebo-controlled study was conducted on 65 participants aged 18 to 60 years having 2 or more allergic symptoms like sneezing, rhinorrhoea, nasal obstruction, and nasal itching for a cumulative period greater than 1 hour per day. The study participants received a capsule of Nigella Sativa Oil (250 mg) with 2.5 mg piperine (BioPerine) as a bioavailability enhancer or a placebo, twice a day, after food for 15 days. The primary objectives were evaluated by mean change in Total Nasal Symptom Score and the duration of AR symptoms per day from baseline to Day 15. Secondary endpoints were changes in Total Ocular Symptoms Score, AR symptom frequency and severity, serum Immunoglobulin E levels, and Patient Global Impression of Change scale. Adverse events were monitored throughout the study.
Effective and well-tolerated : the outcomes of this study suggested a positive impact of NSO standardized for 5% TQ (Nigellin® Amber) in allergic rhinitis caused by seasonal allergens, . Further studies in larger populations in different ethnic backgrounds will help to position NSO as an effective and safe supplement to manage the symptoms of AR.
A randomized, double-blind, placebo-controlled study to evaluate the benefits of a standardized Nigella sativa oil containing 5% thymoquinone in reducing the symptoms of seasonal allergy
Medicine 103(32):p e39243, August 09, 2024
Anju Majeed, Shaheen Majeed, Avinash Kadasiddappa Parameswarappa, Avinash Murali, Satish Gudimallam, Chikkalingaiah Siddegowda, Harshith Chandrashekar, Lakshmi Mundkur.