Standardized Ashwagandha Root Extract alleviates stress, anxiety, and improves quality of life
In the present study, Sabinsa used a standardized extract of ashwagandha,and evaluated the efficacy and safety of this extract in improving the quality of life in healthy adults with stress and anxiety.
In the present study, Sabinsa used a standardized extract of ashwagandha, prepared from dried roots, containing 2.5% withanolides (Shagandha®), and analyzed by using a USP monograph (HPLC), and evaluated the efficacy and safety of this extract in improving the quality of life in healthy adults with stress and anxiety.
The result of this study suggests that ARE (Shagandha, standardized for 2.5% withanolides) at 500 mg with 5 mg of 95% piperine once a day could induce positive effects on stress and anxiety and improve the quality of life in healthy individuals with mild to moderate stress. A significant improvement could be observed in cognitive tasks, multitasking, and concentration in comparison to placebo.
The results of the study were comparable to earlier studies conducted with ashwagandha extracts containing a higher quantum of withanolides.
Sabinsa offers ashwagandha extract (7% Withanolides by gravimetry, Whitaferin A by HPLC), as well as a specific grade named Shagandha®, standardized to 2.5% withanolides and 0.25% withaferin A, analyzed according to the monograph of the United States Pharmacopeia (USP) (HPLC).
With Shagandha™, Sabinsa ensures the authenticity of its ashwagandha extract by complying with the US Pharmacopoeia-National Formulary (USP-NF) monograph. The company selected a botanical specialist to test the ingredient and confirm its compliance with the USP monograph.
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A preclinical study was published in 2020 "Aphrodisiac composition and management of male sexual dysfunction", also patented, and a study is underway to assess the efficacy and safety of Shagandha® in improving the quality of life of adults. healthy man suffering from stress and anxiety.
"A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones"
Results from a randomized, double-blind, placebo-controlled study - Medicine (2023) 102:41
Muhammed Majeed, Kalyanam Nagabhushanam, Lakshmi Mundkur