SlimNat® : Feel the slimming effect

Becarre natural

SlimNat is Nektium's proprietary low caffeine, green coffee bean extract manufactured exclusively with hydro alcoholic extraction process. The process ensures a minimum of 45% chlorogenic acids content and over 25% of 5-caffeoylquinic acid (5-CQA) by UPLC. Chlorogenic acids may help regulate blood glucose levels, and improve lipid metabolism and obesity by multiple mechanisms.

SlimNat : simplified process, low ethanol

Fig.1 - SlimNat is extracted using low ethanol exclusively


SlimNat : 45% Clorogenic, 25% 5-CQA

Fig.2 - SlimNat brings 45% Chlorogenic acids and more than 25% 5-Caffeoylquinic Acid (5-CQA)


SlimNat : comparison Raw material and SlimNat

Fig.3 - an excellent correlation is observed between the Coffea arabica beans raw material and Slimnat


Effect on weight and fat reduction

Fig.4 - Effect on weight and fat reduction (modified from Vinson (2012) Diabetes Metab Syndr Obes 5:21-7)

Excess weight,
a serious health problem

According to WHO obesity and overweight have become a world pandemic: In 2005 approximately 1.6 billion adults (age over 15) were estimated to be overweight and at least 400 million adults were obese, with further projections of 2.3 billion adults overweight and more than 700 million obese by 2015. Excess weight carries serious health problems such as cardiovascular disease, diabetes, musculoskeletal disorders and some cancers (WHO (2006) Fact sheet Nº311).

Slimnat,
innovative weight management

Body weight regulation represents a complex, substantial challenge; although it depends ultimately upon the balance between energy intake (food) and energy expenditure (heat production and physical activity) many redundant pathways control energy regulation. This redundancy means that attacking excess weight (accumulation of energy) through a single mechanisms usually fails as the body will tend to compensate activating these other pathways (Foster-Schubert (2006) Endocrine Reviews 7:779-793).

Presevative and gentle process

Slimnat is the low caffeine hydroalcoholic (exclusively water / ethanol (see Figure 1)) Coffea arabica extract manufactured by Nektium, standardized to a minimum of 45% chlorogenic acids keeping the amount of 5-caffeoylquinic acid (5-CQA) over 25% (see Figure 2). Chlorogenic acids are one of the most abundant polyphenols in the human diet and are typically found in food sources such as coffee, fruits and vegetables. The image above shows the chromatographic profiles obtained for the Coffea arabica beans employed as the raw material and the standardized extract Slimnat. An excellent correlation is observed between the Coffea arabica beans raw material and Slimnat (see Figure 3), indicating that the natural ratios between the different phytoactive compounds are preserved during the extraction and manufacturing process.

Becarre Natural

 
Recommended dosage : 700 mg a day
Safety & Quality : Slimnat is manufactured according to Good Manufacturing Practices and all EC applicable regulations. All ingredients are of vegetable origin. The product is non-GMO, non-irradiated, and allergen and BSE free.

Mice fed with standardized green coffee extract (GCE) for 14 days showed a tendency to reduced visceral fat, body weight and hepatic triglycerides accumulation. Significant reductions were observed in body weight, body mass index, and percent body fat with no significant changes to diet in 16 overweight individuals taking GCE during a 22-week crossover study. A meta-analysis of 3 out of 5 eligible clinical trials in weight loss using GCE showed a significant difference in body weight in favor of the extract. In a multicenter, randomized, double-blind, placebo-controlled, parallel group study in 117 male volunteers with mild hypertension significant reductions in systolic blood pressure were reported in those taking 93 and 185mg of GCE after 28 days. Results were further replicated in another randomized controlled trial in 28 individuals taking 140mg of the extract (all refs available).


Gontran Gaillot